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Bleeding Disorders Awareness Month, formerly Hemophilia Awareness Month, focuses on the genetic blood disease that prevents blood from clotting usually. Due to its prevalence in monarchies, Hemophilia earned the nickname "Royal Disease."
Queen Victoria of England (1837-1901) was a carrier of the hemophilia gene. Her eighth child Leopold suffered from frequent bleeding, which was reported in the British Medical Journal in 1868.
Hemophilia has been known for thousands of years. The Talmud, a collection of Jewish rabbinical writings from the second century of the Common Era, notes exempts male babies from circumcision if two brothers had already died from the procedure.
By the 1990s, the safety and efficacy of factor concentrate improved.
In 1992, the first recombinant factor VIII product received approval from the Food and Drug Administration (FDA).
In 1997, factor IX products captured FDA approval. Additional synthetic drugs, including desmopressin acetate (DDAVP), which treat mild-to-moderate Hemophilia A and Von Willebrand disease, also were introduced.
By the mid-1990s, prophylactic (a preventative treatment regimen) therapy in children with hemophilia became more common. Since the advent of prophylaxis, children could look forward to a life of less pain due to chronic bleeding.
Today, hemophiliac children attain long, healthy, and active lives.
This event first occurred in 1986.
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